As a viral pandemic spreads across America, Wade Vogel (Arnold Schwarzenegger) searches for his runaway daughter Maggie (Abigail Breslin) and finds her in the quarantine wing of a hospital. Wade brings his daughter back home to his family for the short time before the teenager begins a painful metamorphosis.
Determined to hold onto his precious daughter as long as he can and refusing to hand her over to the local police Wade edges ever closer to a time where he will have to take matters into his own hands.
